Isopure Nutrition Facts (2026): Zero Carb Whey Protein Isolate & Isopure Clear, Every Number Verified

Isopure’s whey isolate line — the powder and the Isopure Clear bottle — is built around one number: zero. Zero carbs, zero sugar, zero fat, in both formats. The powder delivers 25g of protein at 110 calories per scoop, a 22.7g-per-100-calorie ratio; Isopure Clear delivers 32g of protein at 130 calories per 16.9 fl oz bottle, a 24.6g-per-100-calorie ratio that is the highest of any mainstream ready-to-drink protein shake we have verified, ahead of Fairlife Nutrition Plan’s 20.0g per 100 calories and Premier Protein’s 18.8g. Isopure has been on retail shelves for more than two decades under parent company Glanbia Nutritionals, and its whey isolate is further-filtered to strip out residual lactose, which is why it turns up repeatedly across our other nutrition guides as the reference point for “true zero-carb” and “highest protein density.” Every number below is drawn from Isopure’s own published 2026 label data; anything we could not confirm is shown as “—.”

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Isopure Zero Carb Whey Protein Isolate Powder: Full Label

One scoop is approximately 32g of powder. Figures below are read from Isopure’s published 2026 label for the Zero Carb 100% Whey Protein Isolate line, which is also sold under the “Low Carb” name on some retail listings — every source we verified shows identical macros (25g protein, 0g carbs, 0g sugar) across both names, so this appears to be the same core formulation.

Sodium, cholesterol, and micronutrient figures were not independently confirmed for this guide and are omitted rather than estimated. Scoop weight and serving count vary slightly by flavor and container size.

Isopure Zero Carb 32g Clear (Ready-to-Drink): Full Label

Isopure Clear is a transparent, fruit-flavored whey isolate drink rather than a milky shake — the whey has been ultra-filtered to remove both lactose and fat, which is why it pours clear. Sold in 16.9 fl oz bottles, typically as a 12-pack, in flavors including Apple Melon, Grape Frost, Alpine Punch, and Blue Raspberry.

Isopure Powder vs Dymatize ISO100 vs Transparent Labs vs Optimum Nutrition Gold Standard

All figures are per single manufacturer scoop, read from each brand’s own published 2026 label.

Isopure’s 0g of sugar and 0g of carbs is the clear differentiator in this table — every other pick here carries at least 1g of sugar per scoop, and none is a true zero-carb formula. The trade-off is calorie efficiency versus Dymatize: Isopure’s protein-per-calorie ratio (22.7g/100 cal) beats Dymatize ISO100 (20.8g/100 cal) and Optimum Nutrition Gold Standard (20.0g/100 cal), though Transparent Labs’ larger 28g scoop lands close behind at 21.5g/100 cal. For lifters who rely on a post-workout shake for glycogen replenishment as well as protein, a true zero-carb powder like Isopure delivers none of that — pair it with a carb source separately. See our full best whey protein isolate ranking for the complete field, and our Dymatize ISO100 nutrition facts breakdown for the hydrolyzed alternative.

Isopure Clear vs Fairlife Nutrition Plan vs Premier Protein vs Core Power Elite vs OWYN Pro Elite

All figures are per bottle, read from each brand’s own published 2026 label.

Isopure Clear leads this entire field on protein density — 24.6g per 100 calories, ahead even of Fairlife Nutrition Plan’s 20.0g, because stripping out the milk fat and lactose that a dairy-based shake carries removes calories without touching the protein count. Core Power Elite delivers the most total protein in one bottle (42g) but at 230 calories, more of a meal-replacement format than a light shake. OWYN Pro Elite is the only plant-based pick here and ties Isopure Clear on total protein (32g), but its 200-calorie count puts it at the bottom of this table on protein-per-calorie. For a full breakdown of OWYN’s allergen-free formulation, see our OWYN protein shake nutrition facts guide, and for the complete ready-to-drink field see our best protein drinks of 2026 ranking.

What Isopure Costs

• Isopure Zero Carb / Low Carb powder: a 3lb bag (42 servings) runs approximately $89.75, or about $2.14 per scoop — roughly $0.085 per gram of protein. That is one of the more expensive powders per gram in our price-per-gram comparisons, in the same tier as Ghost, and well above budget picks like Kirkland Signature at a warehouse club. You are paying for the zero-carb, zero-sugar formulation and the further lactose filtration, not a cheaper way to hit a protein target.
• Isopure Clear: approximately $3.75 per 16.9 fl oz bottle, typically sold as a 12-pack. That undercuts nothing — ready-to-drink shakes across the board run $2.30–$2.70 per bottle for Fairlife and Premier Protein — but Isopure Clear is the only one in that price range with 0g of sugar and a genuinely clear, non-milky texture.

For the full field ranked strictly by price per gram of protein, see our cheapest high-protein snacks by price per gram guide.

Who Isopure Is For

Choose Isopure Zero Carb powder if: you are on a strict ketogenic or low-carb diet and want a shake that contributes exactly 0g of carbs to your daily count; you are optimizing a cutting protocol for maximum protein-per-calorie; or you are lactose-sensitive and want the extra filtration on top of standard whey isolate’s already-low lactose content.

Choose Isopure Clear if: you want a ready-to-drink shake that does not taste or feel like a milkshake — it is closer to a fruit-flavored sports drink with 32g of protein folded in; you want the single highest protein-per-calorie ready-to-drink option on the market; or a dairy-shake texture (Fairlife, Premier Protein, Core Power) is simply not something you enjoy drinking daily.

Consider an alternative if: you rely on your post-workout shake for carbohydrate replenishment as well as protein (a true zero-carb formula gives you none, so pair it with fruit or oats); you dislike sucralose (Isopure uses it in both formats, as do Dymatize and most Fairlife products); or price per gram of protein is your primary constraint, in which case Kirkland Signature or Dymatize ISO100 on sale will beat Isopure’s cost.

Frequently Asked Questions

How much protein is in Isopure?

Isopure Zero Carb powder delivers 25g of protein per scoop (110 calories, 22.7g protein per 100 calories). Isopure Clear, the ready-to-drink bottle, delivers 32g of protein per 16.9 fl oz bottle (130 calories, 24.6g protein per 100 calories) — the highest protein-per-calorie ratio of any mainstream ready-to-drink protein shake we have verified.

Is Isopure actually zero carb?

Yes, for both formats covered here. Isopure Zero Carb powder and Isopure Clear both show 0g total carbohydrates, 0g sugar, and 0g fat on their published labels. That makes them a fit for strict ketogenic or low-carb diets, with the trade-off that neither contributes any carbohydrate energy for glycogen replenishment after a workout.

Is Isopure lactose-free?

Both formats are further-filtered specifically to strip out residual lactose beyond what standard whey protein isolate already removes, which is why Isopure is commonly recommended as a whey option for lactose-sensitive people who still react to regular whey isolate. It is filtered, not certified allergen-free — anyone with a diagnosed milk allergy (as opposed to lactose intolerance) should still avoid whey-based products.

How does Isopure compare to Dymatize ISO100?

Both deliver 25g of protein per scoop, but Isopure Zero Carb runs 110 calories with 0g sugar versus Dymatize ISO100’s 120 calories with 1g of sugar, giving Isopure a slightly better 22.7g-per-100-calorie ratio versus 20.8g. Dymatize is hydrolyzed for faster amino-acid absorption, which Isopure is not; Isopure is the more calorie-efficient and zero-carb option. See our Dymatize ISO100 nutrition facts guide for the full hydrolyzed-whey breakdown.

Is Isopure Clear better than Fairlife Nutrition Plan?

It depends on the goal. Isopure Clear is more protein-dense (24.6g per 100 calories versus Fairlife’s 20.0g) and carries 0g of sugar versus Fairlife’s 2g, plus a lighter, non-milky texture. Fairlife Nutrition Plan delivers slightly more total protein relative to its smaller bottle size profile and is more widely stocked at conventional grocery chains. Choose Isopure Clear for calorie efficiency and a clear texture; choose Fairlife for wider availability and a milkshake-style drink.

Bottom line: Isopure earns its reputation on one consistent trait across both formats — zero carbs, zero sugar, zero fat, verified on the label every time. The powder’s 25g of protein at 110 calories (22.7g per 100 cal) beats Dymatize ISO100 and Optimum Nutrition Gold Standard on calorie efficiency, and Isopure Clear’s 32g of protein at 130 calories (24.6g per 100 cal) is the most protein-dense ready-to-drink shake in our comparisons, ahead of Fairlife Nutrition Plan and Premier Protein. Both cost more per gram of protein than budget picks like Kirkland Signature, and neither format replaces the carbohydrates a post-workout shake can otherwise provide — the honest trade-offs for a genuinely zero-carb whey isolate. For the full powder field, see our best whey protein isolate of 2026 guide; for the full shake field, see our best protein drinks of 2026 ranking. Browse the complete protein snacks directory for every verified option.